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1.
BMC Pregnancy Childbirth ; 24(1): 3, 2024 Jan 02.
Artículo en Inglés | MEDLINE | ID: mdl-38166924

RESUMEN

BACKGROUND: The research was conducted to evaluate the birth and newborn outcomes of Syrian immigrant women according to maternal age groups and Vitamin D use. METHODS: It was conducted retrospectively using the birth records of 2,866 Syrian migrant women, who had given birth at a tertiary center between January 2016 and May 2020. Demographic features, obstetric and neonatal outcomes were analyzed according to age groups and Vitamin D use. RESULTS: The mean age of the patients included in the study was 26.22 ± 5.90, the mean gestational age at birth was 38.06 ± 2.1 weeks, and the mean newborn birth weight was 3.151 g. The mean hemoglobin value of the patients was 11.55 ± 1.54. While most of the patients were taking iron supplements (80.59%), Vitamin D (Vit D) supplement intake was 38.31%. The mean number of antenatal follow-ups was 3.40 ± 1.65. While the most common delivery method was normal vaginal delivery (61.93%), cesarean section rates were found to be 38.07%. The need for blood transfusion was significantly lower in the group that had received Vitamin D than that in the group that had not received it (2.00% vs. 8.94% p < 0.001). The rate of preterm birth was found to be 5.74% in the group that had received Vitamin D and 9.28% in the group that had not received it, which was significantly higher (p < 0.001). CONCLUSIONS: We have seen that maternal and fetal outcomes can be improved with hospital follow-up and adequate vitamin supplements in refugee pregnant women.


Asunto(s)
Nacimiento Prematuro , Refugiados , Femenino , Humanos , Recién Nacido , Embarazo , Cesárea , Resultado del Embarazo/epidemiología , Nacimiento Prematuro/epidemiología , Estudios Retrospectivos , Siria , Turquía/epidemiología , Vitamina D , Vitaminas
2.
BMC Med Educ ; 24(1): 60, 2024 Jan 12.
Artículo en Inglés | MEDLINE | ID: mdl-38216913

RESUMEN

BACKGROUND: Dietary habits are crucial for maintaining overall health and have been shown to impact academic performance. However, little research has been conducted on the specific eating, drinking, and smoking habits during the exam period and their effect on academic performance. Therefore, this study aimed to investigate dietary and smoking habits and their relationship with academic performance among medical students at Damascus University. Findings from this study can inform interventions to improve both dietary habits and academic performance. METHODS: A cross-sectional design was used to investigate the association between dietary habits during the exam period and academic performance among 608 medical students. Data were collected using a self-administered paper-based questionnaire that was randomly distributed across multiple classes. The statistical analysis employed Spearman's rank correlation and multiple linear regression to examine the relationship between the different amounts of diet behaviour during the exams and the reported average students' grades from the last two semesters. The regression model was adjusted for age, sex, residency type, and residency partners. RESULTS: In both Spearman's rank correlation and multiple linear regression analyses, we observed consistent negative associations between specific dietary habits and self-reported average grades. These included daily consumption of tea (B = -0.334, p = 0.022), instant coffee (B = -0.682, p = 0.001), and weekly fast food consumption (B = -0.583, p = 0.038). Notably, traditional coffee was found to be significant in the Spearman analysis but did not exhibit significance in the regression analysis. Furthermore, the regression analysis revealed a negative association between water pipe consumption and academic performance (B = -0.700, p = 0.049). No significant association was observed between other dietary habits, cigarette smoking, and academic performance. CONCLUSIONS: The study highlights a negative, but weak, association between academic achievement and specific dietary habits during the exam period. However, further longitudinal studies are needed to establish causal relationships. Additionally, the study suggests exploring the impact of other habits such as study and sleeping habits, which may have a more significant impact on academic achievement.


Asunto(s)
Éxito Académico , Estudiantes de Medicina , Humanos , Estudios Transversales , Café , Siria , Dieta , Fumar
3.
Child Dev ; 95(3): e206-e223, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38108194

RESUMEN

Refugee children are at increased risk for mental health problems, including post-traumatic stress, depression, and externalizing problems. The refugee environment, maternal mental health, and parenting may reduce or exacerbate that risk. This study investigated their direct and indirect associations with child mental health cross-sectionally in a sample of Syrian refugee child-mother dyads in Lebanon in 2017-19. Mediating pathways were tested using structural equation modeling with 1446 dyads (child: Mage = 11.39, 52.1% females) and again 1 year later with 872 (child: Mage = 12.17, 53.1% females) of the original sample. Mediating pathways from the refugee environment through maternal mental health and parenting to child outcomes were detected, emphasizing the importance of a holistic approach to refugee mental health.


Asunto(s)
Refugiados , Trastornos por Estrés Postraumático , Femenino , Humanos , Masculino , Madres/psicología , Salud Mental , Refugiados/psicología , Siria , Trastornos por Estrés Postraumático/psicología
4.
Curr Psychiatry Rep ; 25(12): 857-863, 2023 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-37943430

RESUMEN

PURPOSE OF REVIEW: This critical review primarily aims to conduct a comprehensive assessment of recent studies conducted within the past 3 years, with a specific focus on the use of art therapy within Syrian child and adolescent refugee populations. The central objective of this inquiry is to explore the impact of art therapy interventions and provide critical insights into their effectiveness in enhancing the mental well-being and resilience of these young refugees. RECENT FINDINGS: Recent research conducted within the past 3 years highlights the effectiveness of art therapy as an intervention strategy within Syrian child and adolescent refugee populations. These studies emphasize that art therapy offers a safe and supportive space for these young refugees to express emotions, process trauma, and improve their psychological well-being. It has shown promise in mitigating trauma-related challenges and fostering resilience among this group of refugee populations. Furthermore, art therapy plays a crucial role in preserving cultural identities and has proven to be versatile and adaptable to various artistic modalities. These findings underscore the potential of art therapy as a valuable tool for supporting the mental well-being and resilience of Syrian children and adolescent refugees, warranting further exploration and integration into their care and support programs. Recent studies on the use of art therapy within Syrian child and adolescent refugee communities reveal its potential as a powerful intervention strategy for enhancing mental well-being and resilience in this vulnerable population. The review identifies six key themes, highlighting the therapeutic benefits and versatility of art therapy. As we move forward, these findings offer promising future directions for research and practice in art therapy with this specific group of refugees, emphasizing the need for continued exploration and integration of this approach in supporting Syrian child and adolescent refugees.


Asunto(s)
Arteterapia , Refugiados , Resiliencia Psicológica , Niño , Humanos , Adolescente , Refugiados/psicología , Bienestar Psicológico , Siria
5.
BMJ Open ; 13(7): e064851, 2023 07 20.
Artículo en Inglés | MEDLINE | ID: mdl-37474187

RESUMEN

OBJECTIVES: To provide an overview of the holistic impact of the armed conflict on medical education and health professionals' training (MEHPT) in Syria. SETTING: Syria is a country which underwent an armed conflict for 10 years and suffered from the weaponisation of health. METHODS: A mixed-methods systematic review including quantitative, qualitative, mixed-methods and textual literature between 2011 and 2021 including papers on the Syrian MEHPT undergraduate and postgraduate education and training personnel (including medicine, dentistry, pharmacy, nursing, midwifery and allied health professionals). The electronic search was conducted in October 2018 in Embase, Global Health, Medline, PsycINFO, Web of Science, PubMed, Scopus, CINAHL and grey literature. And an update to the search was conducted in August 2021 in PubMed, Google Scholar and Trip database. OUTCOMES: The impact of conflict on the MEHPT system, personnel, experiences, challenges and channels of support. RESULTS: Of the 5710 citations screened, 70 met the inclusion criteria (34 quantitative, 3 qualitative, 1 mixed-method, and 32 reports and opinion papers). The two major cross-cutting themes were attacks on MEHPT and innovations (present in 41% and 44% of the papers, respectively), followed by challenges facing the MEHPT sector and attitudes and knowledge of trainees and students, and lastly health system and policy issues, and narrating experiences. CONCLUSION: Conflict in Syria has politicised all aspects of MEHPT. Influenced by political control, the MEHPT system has been divided into two distinguished geopolitical contexts; government-controlled areas (GCAs) and non-GCAs (NGCAs), each having its characteristics and level of war impact. International and regional academic institutes collaboration and coordination efforts are needed to formulate educational platforms using innovative approaches (such as online/blended/store-and-forward/peer-training/online tutoring) to strengthen and build the capacity of the health workforce in conflict-affected areas.


Asunto(s)
Educación Médica , Personal de Salud , Humanos , Siria , Personal de Salud/educación , Técnicos Medios en Salud , Conflictos Armados
6.
Med Confl Surviv ; 39(3): 229-246, 2023 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-37122087

RESUMEN

The COVID-19 pandemic has increased the burden on the collapsing health system in northwest Syria. The situation was exacerbated by the low rates of adherence to preventive measures and acceptance of the COVID-19 vaccine. In this study, we systematically analysed studies related to Risk Communication and Community Engagement programs, and community awareness in northwest Syria in order to determine the most widespread prevention methods, the community's perspectives and knowledge of epidemic prevention, and the factors that prevent effective community engagement and uptake of COVID-19 prevention precautions in an area that has been suffering from the scourge of conflict for more than ten years. Based on the research findings, low adherence to COVID-19 prevention measures is mainly due to external factors related to socioeconomic status, scarcity of resources, and poor living conditions. Therefore, this study suggested that integrated multi-sectoral humanitarian programs that address these factors holistically are more effective than solely public health interventions in involving the community to become an active part of the Risk Communication and Community Engagement programs and ensuring their effectiveness.


Asunto(s)
COVID-19 , Humanos , COVID-19/prevención & control , Vacunas contra la COVID-19 , Pandemias/prevención & control , Siria , Salud Pública
7.
Pediatrics ; 151(Suppl 2)2023 05 01.
Artículo en Inglés | MEDLINE | ID: mdl-37125885

RESUMEN

OBJECTIVES: In 2019, >71 million children aged <5 had spent their entire lives in conflict-affected settings. Compounding adversities including violence, poverty, and displacement have immediate and long-term effects on early childhood development, health, behavior, and well-being. In response, adaptations of Reach Up have been implemented in conflict and crisis settings. METHODS: This article uses exploratory multiple case study methodology, drawing from implementation and qualitative data from 3 interventions: a mobile phone-based intervention promoting nurturing care among Rohingya and crisis-affected host communities in Bangladesh; Reach Up amid acute violence and displacement in Northeast Syria; and Reach Up group sessions and home visits integrated with health services for an indigenous population in Venezuela. RESULTS: In Bangladesh, tailoring interactive voice response messages improved responsiveness to the developmental needs of young children, yet complementary in-person services were identified as a key program enhancement. In Syria, rapid adaptations of Reach Up addressed the needs of families in acute crisis, including social-emotional learning games for school-aged children. In Venezuela, Reach Up, coupled with complementary lactation counseling, yielded high rates of uptake and satisfaction, and children's language development was highlighted as a key area of growth. CONCLUSIONS: Recommendations to promote early childhood development in crisis and conflict settings include: (1) cultural adaptation based on a holistic understanding of children and caregivers' needs; (2) the integration of child and family safety and linkages with complementary services on the basis of community needs and priorities, and (3) the importance of designing for scale through blended models and costing analyses.


Asunto(s)
Desarrollo Infantil , Aprendizaje , Niño , Femenino , Preescolar , Humanos , Cuidadores , Bangladesh , Siria
8.
Nutrients ; 15(3)2023 Jan 30.
Artículo en Inglés | MEDLINE | ID: mdl-36771406

RESUMEN

Globally, the prevalence of anemia among children during the period of complementary feeding is high. A cross-sectional, mixed-methods study was conducted to examine the main determinants of anemia among Syrian refugee children aged 6 to 23 months (n = 215) and to illuminate the knowledge, attitudes and perceptions of their mothers and Lebanese healthcare staff on its causes and available treatment options. 42% of the children and 20% of their mothers were anemic. Determinants of child anemia were the mother having anemia or not knowing that fish/seafood is a source of iron; the child having been acutely ill the last two weeks or receiving cow's milk, but not consuming iron-rich infant formula, added fats/oils, or fruits in the previous 24 hours. Several Syrian mothers knew some causes of anemia and named dizziness as a leading symptom but did not mention flesh foods as a key source of heme iron. They reported financial constraints in accessing iron-rich foods and supplements. Lebanese doctors largely gave appropriate dietary advice and prescribed iron supplements as treatment. Multisectoral interventions are needed that combine medical and financial support with nutrition counseling for mothers to reduce the high burden of anemia among young children living in a multiple crises situation.


Asunto(s)
Anemia , Refugiados , Humanos , Femenino , Animales , Bovinos , Madres/psicología , Refugiados/psicología , Líbano/epidemiología , Estudios Transversales , Siria , Anemia/epidemiología , Hierro , Atención a la Salud
9.
Int J Qual Stud Health Well-being ; 18(1): 2170010, 2023 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-36744740

RESUMEN

The COVID-19 pandemic's impact varies between and within nations, causing new forms of inequality. Refugee and orphan children in conflicted areas are more likely to suffer due to poverty, vulnerability, and limited access to essential services including reduction in donor funding. This qualitative study is the first to assess the effects of the COVID-19 pandemic and the financial crisis on Iraqi and Syrian orphaned children and their mothers. The Modified Grounded Theory was used for the preliminary analysis to expand the range of themes. This study has identified five major themes: financial crisis, low educational attainment, child labour, mental health issues, violence, and social problems. The impact of COVID-19 children and adolescents' mental health is of great concern. These multiple crises may significantly impact orphan children and adolescents' cognitive, mental health, and physical development. It is critical to address mental health issues during the current crisis and to plan for possible future pandemics and their intersecting outcomes. A Holistic approach requires providers to be aware of their clients' intersecting circumstances and needs using a range of lenses, including the person in the environment, family dynamics, culture, politics, and structural challenges. Offering food, medical supplies, and housing are considered basic needs.


Asunto(s)
COVID-19 , Niños Huérfanos , Niño , Adolescente , Humanos , Siria , Niños Huérfanos/psicología , Irak , Pandemias
10.
Sex Reprod Healthc ; 35: 100823, 2023 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-36796309

RESUMEN

OBJECTIVE: To describe Syrian women's experiences of being pregnant and receiving care at antenatal clinics for the first time after migration. METHODS: A phenomenological lifeworld approach was used. Eleven women from Syria enrolled at antenatal clinics, who were experiencing their first pregnancy in Sweden but who may have given birth before in other countries, were interviewed in 2020. The interviews were open and based on one initial question. Data were inductively analysed using a phenomenological method. RESULTS: The essence of Syrian women's experiences of being pregnant and receiving care at antenatal clinics for the first time after migration was the importance of being met with understanding to create trust to build a sense of confidence. The following four constituents capture the essence of the women's experiences: "It was important to feel welcomed and to be treated like an equal"; "A good relationship with the midwife strengthened self-confidence and trust"; "Good communication despite language difficulties and cultural differences was important"; and "Previous experience of pregnancy and care influenced the experience of the care received". CONCLUSION: Syrian women's experiences reveal a heterogeneous group with different experiences and background. The study highlights the first visit and emphasises the importance of this visit for future quality of care. It also points out the negative occurrence of the transferring guilt from the midwife to the migrant woman in case of cultural insensitivity and clashing norm systems.


Asunto(s)
Partería , Parto , Embarazo , Femenino , Humanos , Siria , Suecia , Partería/métodos , Comunicación , Investigación Cualitativa , Atención Prenatal/métodos
11.
Pediatr Nephrol ; 38(8): 2699-2709, 2023 08.
Artículo en Inglés | MEDLINE | ID: mdl-36662300

RESUMEN

BACKGROUND: Pediatric urinary stone disease (USD) is a costly medical problem. This study aims to assess the clinical characteristics and outcomes of common and rare causes of pediatric USD. METHODS: A retrospective descriptive cohort study included all children < 13 years of age with confirmed USD admitted to the Children's University Hospital in Damascus, Syria, from January 2013 to December 2019. The study sample was divided into two groups based on etiologies: common and rare causes groups. RESULTS: We evaluated 235 patients; 147 of them were males, and the male-to-female ratio was 1.7:1. The common causes group consisted of 203 patients (mean age 3.52 ± 3.66 years) and mainly included metabolic disorders (45.5%) and anatomical abnormalities (22.3%), while the rare causes group included 32 cases (mean age 4.93 ± 4.08 years), 12 patients with uric acid stones (37.5%), 7 patients with cystinuria (21.9%), and primary hyperoxaluria in 5 patients (15.6%). In addition, 39.6% of study patients were born to consanguineous marriages. Sixty-two patients developed AKI, and eleven patients had chronic kidney disease (CKD). Patients with rare causes were more likely to have AKI, CKD, bilateral stones, and recurrent stones (P-value < 0.05). Stone analysis was performed on 83 patients, and the main stone types were calcium oxalate (34.9%), uric acid (14.4%), and struvite stones (12%). Surgery was the most performed treatment in 101 patients (56.7%). CONCLUSION: Patients with rare causes of pediatric USD are at a higher risk for severe complications and require early diagnosis and management. The high rate of uric acid stones in our society requires further evaluation for possible underlying causes. A higher resolution version of the Graphical abstract is available as Supplementary information.


Asunto(s)
Lesión Renal Aguda , Cálculos Renales , Nefrolitiasis , Cálculos Urinarios , Urolitiasis , Humanos , Masculino , Niño , Femenino , Preescolar , Lactante , Siria/epidemiología , Estudios Retrospectivos , Estudios de Cohortes , Ácido Úrico , Cálculos Urinarios/epidemiología , Cálculos Urinarios/etiología , Urolitiasis/diagnóstico , Urolitiasis/epidemiología , Urolitiasis/etiología , Nefrolitiasis/complicaciones , Lesión Renal Aguda/complicaciones , Cálculos Renales/etiología
12.
BMC Ophthalmol ; 23(1): 17, 2023 Jan 10.
Artículo en Inglés | MEDLINE | ID: mdl-36627615

RESUMEN

BACKGROUND: The main way to prevent blindness from Glaucoma is by early detection and diagnosis; and to do so the awareness must be raised among people where Glaucoma is defined as an acquired chronic optic neuropathy characterized by optic disk cupping and visual field loss. Lack of knowledge about this disease is one of the most important reasons that made it develop to advanced stages. Based on that, we conducted scientific research to assess peoples' awareness and knowledge about Glaucoma. After reviewing the literature, it was found that this study is the first in Syria. METHODS: We conducted a cross-sectional study in May 2022. The study included participants, who are above 20 years old, from visitors of Al-Mouwasat University Hospital in Damascus, Syria. During one week, Data was gathered according to the questionnaire, which was presented through face-to-face interviews with participants. We have allocated one point (1) to each question. Three levels of knowledge were adopted, namely; weak level from (0) to (3), average level from (4) to (7) and good level from (8) to (11). Associations between participants' demographic and other details were tested using Chi-square test and other tests, and a p-value of < 0.05 was considered significant. RESULTS: A total of 500 participants were interviewed. For awareness of Glaucoma, 33.6% of the participants (n = 168) had heard of Glaucoma, and 66.4% hadn't (n = 332). Mean test results for the knowledge of Glaucoma was 1.62 out of 11, and only 8% of participants (n = 40) had a good knowledge of Glaucoma. Education Level, governorate, and department of hospital that the patient came for significantly affected the knowledge of Glaucoma. Moreover, hospital, Ophthalmologists' Clinics, and health staff (M = 5.45) were the better Resource for information than family, relatives, and friends (M = 3.16). Finally, social media and the Internet group had the lowest mean test results (M = 1.23). These test results were significant, with a p-value < 0.001. CONCLUSION: The percentage of knowledge and awareness was significantly low. Organized community awareness methods must disseminate more ability to increase the general public's understanding to avoid injury and late diagnosis of Glaucoma.


Asunto(s)
Glaucoma , Disco Óptico , Humanos , Adulto Joven , Adulto , Estudios Transversales , Siria , Glaucoma/diagnóstico , Hospitales Públicos , Conocimientos, Actitudes y Práctica en Salud
13.
Appl Radiat Isot ; 190: 110478, 2022 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-36257130

RESUMEN

The interpretation of aerial gamma ray spectrometry in term of geological and environmental analysis is undertaken herein through applying a specific methodology including different radioactive and statistical techniques for characterizing the sedimentary and environmental conditions of the Al-Rassafeh Badyieh (Area-2), Syria. The radioactive technique uses the uranium favorability index (UI) and alteration(F) parameters, that are evaluated through analyzing the relationships between eU, eTh, K and their ratios (eTh/eU, eU/eK, and eTh/eK) for the nine scored lithological units already determined in the study area. The statistical technique applies the non linear multifractal approach with the concentration-number model (C-N) and log-log graphs to differentiate between different radioactive ranges of UI and F parameters. The radioactive element re-distribution, the favorability as regards uranium potentiality, and the degree of uranium remobilization are separately estimated and documented for the nine scored lithological units. Those units show a limited uranium remobilization and redistribution. The sedimentary and environmental conditions of the Area-2 are clarified through analyzing the eTh/eU ratio, where marine and continental environments are indicated in the study region.


Asunto(s)
Monitoreo de Radiación , Contaminantes Radiactivos del Suelo , Uranio , Uranio/análisis , Contaminantes Radiactivos del Suelo/análisis , Monitoreo de Radiación/métodos , Rayos gamma , Siria , Espectrometría gamma/métodos
14.
Int Breastfeed J ; 17(1): 37, 2022 05 14.
Artículo en Inglés | MEDLINE | ID: mdl-35568877

RESUMEN

BACKGROUND: Adequate breastfeeding and complementary feeding practices are paramount in fragile situations where access to food and healthcare is limited. The objectives of this study are to examine breastfeeding and complementary feeding practices among Syrian refugees and their Lebanese host communities and to investigate the correlates of exclusive breastfeeding (EBF) at four and 6 months in these communities. METHODS: Using two-stage stratified sampling, a cross-sectional survey was conducted in Akkar, a region with a high density of Syrian refugees in Lebanon, between April and November 2019. In one-to-one interviews, mothers of children (6-24 months) completed a questionnaire including specific questions about breastfeeding and complementary feeding practices, a 24-h recall, and socio-demographic characteristics for 189 Syrian refugees and 182 Lebanese host community households. Descriptive statistics, simple and multiple logistic regression were used in data analysis. RESULTS: Among breastfeeding practices, ever-breastfeeding was most prevalent (90%), followed by early initiation of breastfeeding (64.8%), EBF at four (49.6%), and six (36%) months. One in four children was introduced to solids before 6 months of age, and less than a third was given iron-fortified baby cereals as the first complementary foods. Only 24.4% and 9.2% of children met the minimum dietary diversity and minimum acceptable diet requirements, respectively. Compared to children of the Lebanese host communities, those of Syrian refugees had higher rates of EBF at four and 6 months as well as continued breastfeeding at 1 year, whereas only 17.9% of Syrian refugees' children met minimum dietary diversity compared to 30.9% of Lebanese host community children (p <  0.05). Among refugees, education and spouse's employment status were associated with higher odds of EBF at 4 months. As for Lebanese households, female children were less likely to be exclusively breastfed at 4 months and 6 months, while a natural delivery increased the odds of EBF at 6 months. CONCLUSION: Breastfeeding and complementary feeding practices are suboptimal among children of Syrian refugees and their Lebanese host communities in North Lebanon. There is a need for intervention strategies to tackle gaps in services and assistance delivery programs to enhance infant and young child feeding practices among both communities.


Asunto(s)
Lactancia Materna , Refugiados , Niño , Estudios Transversales , Femenino , Humanos , Lactante , Fenómenos Fisiológicos Nutricionales del Lactante , Líbano , Siria
15.
Arch Physiol Biochem ; 128(4): 887-896, 2022 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-32157917

RESUMEN

The aim of study was to investigate the antidiabetic and antioxidant properties of extracts obtained from dried Prosopis farcta fruit and seeds against streptozotocin-induced diabetes in rats. According to the results, glucose, haemoglobin A1c, α-glycosidase activity, liver and kidney damage biomarkers, and malondialdehyde contents of all of the diabetic groups were found to have increased significantly according to the control group. Furthermore, the insulin and C-peptide secretions increased, and liver malondialdehyde level decreased, which were determined as the result of fluctuations in the antioxidant enzyme activities with a dose of 400 mg/kg fruit extract, while seed extract dosages of 100 and 400 mg/kg caused an increase in hepatic demage biomarkers. It was concluded that fruit extract may have insulin secretion stimulating and lipid peroxidation inhibitory effects, whereas seed extract might have caused hepatocyte damage changes to the transport functions and membrane permeability of these cells, thus causing enzymes to leak.


Asunto(s)
Diabetes Mellitus Experimental , Prosopis , Animales , Antioxidantes/efectos adversos , Biomarcadores , Glucemia , Diabetes Mellitus Experimental/inducido químicamente , Diabetes Mellitus Experimental/tratamiento farmacológico , Frutas , Hipoglucemiantes/efectos adversos , Hígado , Malondialdehído , Extractos Vegetales/efectos adversos , Ratas , Semillas , Siria
16.
Arch Dis Child ; 107(5): 461-467, 2022 05.
Artículo en Inglés | MEDLINE | ID: mdl-34702714

RESUMEN

OBJECTIVE: Protracted international conflict has seen escalating numbers of displaced and resettled Syrian and Iraqi refugees, raising concerns for their health and well-being. This paper describes the demographic and clinical profiles of recently resettled Syrian and Iraqi refugee children and adolescents across physical, psychosocial, developmental and educational domains using standardised multidisciplinary assessments. DESIGN: A cross-sectional observational study was undertaken of initial specialist paediatric multidisciplinary Refugee Health Service assessments completed at the tertiary paediatric hospital (Western Australia) between June 2015 and September 2019. RESULTS: Three hundred and twenty-seven children and adolescents (264 Syrian, 63 Iraqi) were assessed following resettlement. Witnessed trauma (86%) and disclosed adversity (median Refugee Adverse Childhood Experiences score 3, range 1-14) were universally high. Almost all patients had health issues identified across physical (99%), psychosocial (76%) and developmental/educational (75%) domains. Interrupted education (65%) and death of a family member (16%) were significantly associated with psychological morbidities. Common comorbidities included dental caries (78%), non-infectious disease (76%), vitamin D deficiency (72%), malnutrition (46%; overweight/obesity 23%), and psychological (32%; post-traumatic stress disorder 4.3%) and developmental (9.5%) concerns. Emerging and alarming child protection concerns were prevalent (17%), with females demonstrating especially high risks. CONCLUSION: This is the largest comprehensive study demonstrating the complex and cross-dimensional health needs and specific vulnerabilities of resettled Syrian and Iraqi refugee children and adolescents. Early comprehensive standardised multidisciplinary paediatric assessments, and culturally safe, trauma-informed interventions and follow-up are required to optimise resettlement outcomes and promote well-being.


Asunto(s)
Caries Dental , Refugiados , Adolescente , Niño , Estudios Transversales , Femenino , Humanos , Irak/epidemiología , Refugiados/psicología , Siria/epidemiología
17.
BMC Pediatr ; 21(1): 449, 2021 10 11.
Artículo en Inglés | MEDLINE | ID: mdl-34629076

RESUMEN

BACKGROUND: Chylomicron retention disease (Anderson disease) is a result for variant of the SAR1B gene. It is a rare autosomal recessive hereditary disorder with most incidence in infant. It is characterized by lipid malabsorption syndrome with fatty, chronic diarrhea, and growth retardation. CASE PRESENTATION: We report a case of a 19-month Syrian boy who presented with vomiting, growth failure, and chronic, fatty diarrhea. Upper gastrointestinal endoscopy showed whitish appearing duodenal mucosa and small intestinal biopsies revealed steatosis of enterocytes. Genetic testing confirmed chylomicron retention disease with the first description of variant located in the fourth helix of sar1b protein. The patient is treated with nutritional supplements and fat-soluble vitamin supplementation resulting in significant improvement. CONCLUSION: Early endoscopy is recommended in infants with persistent vomiting and failure to thrive due to high suspicion for a disorder of hypocholesterolemia. Early diagnosis and treatment are essential to avoid serious clinical complications, especially neurological impairment.


Asunto(s)
Hipobetalipoproteinemias , Síndromes de Malabsorción , Proteínas de Unión al GTP Monoméricas , Humanos , Lactante , Síndromes de Malabsorción/diagnóstico , Síndromes de Malabsorción/genética , Masculino , Proteínas de Unión al GTP Monoméricas/metabolismo , Siria
18.
Pharm Biol ; 59(1): 778-788, 2021 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-34165371

RESUMEN

CONTEXT: Since ancient times, traditional Arabic medicine (TAM) has been used to treat various diseases in Syria. They are cost-effective with fewer side effects and are more suitable for long-term use compared with chemically synthesized medicines. In addition, the scientific importance is manifested, as this survey proceeds, for the purposes of verifying and documenting these traditional medicines and their common uses. OBJECTIVE: We conducted ethnobotanical and ethnomedicine research on plants traditionally used to treat various diseases in central region of Syria. METHODS: Information was collected from 2019 to 2021 from the cities of Homs and Hama and their villages, which are two governorates located in central Syria, after interviews with traditional practitioners called Attarin, and many other people. Plant specimens were collected according to different references concerning medicinal plants of Syria, to document the traditional uses of plants at least two of the traditional healers and three other people were asked. RESULTS: In this survey, we listed 76 medicinal plants belonging to 39 families in alphabetical order with the parts used and the method of preparation according to their therapeutic use, which are used to treat 106 ailments. CONCLUSIONS: Many of the uses of medicinal plants mentioned in this survey are still under study. There is no doubt that this study will provide new data that could contribute to further pharmacological discoveries by identifying the active ingredients and their mechanism of effect by doing additional pharmacological work to confirm the alleged biological activities of these plants.


Asunto(s)
Etnobotánica/métodos , Etnofarmacología/métodos , Medicina Tradicional/métodos , Plantas Medicinales , Encuestas y Cuestionarios , Adulto , Anciano , Etnobotánica/tendencias , Etnofarmacología/tendencias , Femenino , Humanos , Masculino , Medicina Tradicional/tendencias , Persona de Mediana Edad , Plantas Medicinales/clasificación , Plantas Medicinales/genética , Siria/etnología
19.
Artículo en Inglés | MEDLINE | ID: mdl-33922703

RESUMEN

Lebanon's intersecting economic and political crises exacerbate complex public health issues among both host and refugee populations. This mixed-methods study by a Lebanese service provider, in partnership with an international research institute, seeks to better understand how experiences of gender-based violence (GBV) and mental health intersect in the lives of Syrian and Lebanese women, and how to better meet these needs. It employs a randomized cross-sectional survey of 969 Abaad service users and focus groups with community members and service providers. There were significant associations between GBV and ill mental health; notably, respondents reporting transactional sex had 4 times the likelihood of severe distress (aOR 4.2; 95% CI 1.2-14.8; p ≤ 0.05). Focus groups emphasized less-visible forms of violence, such as emotional violence, and the importance of environmental factors in one's ability to cope, noting "it always came back to the economy". Recommendations include providing a more holistic and coordinated approach between GBV, mental health, livelihood, and basic assistance sectors; and sensitive, accessible, and higher-quality mental health services informed by GBV response actors' experience putting in place survivor-centered programming and made available to both host and refugee community members.


Asunto(s)
Violencia de Género , Refugiados , Estudios Transversales , Femenino , Humanos , Salud Mental , Siria
20.
J Environ Radioact ; 229-230: 106538, 2021 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-33485191

RESUMEN

Transfer factors of radium 226(226Ra), lead 210(210Pb), polonium 210 (210Po), uranium 238 (238U) and thorium 234(234Th) from five different agricultural soils in Syria to coriander, parsley and mint were investigated in a pot culture experiment. Geometric means of transfer factors (TF)were226Ra (0.13),210Pb(0.03), 210Po (0.02) and 238U (1.76) were within worldwide values, while TF values for 234Th (1.35) were higher than those recorded globally. The available transfer factor (ATF) values ranged between 0.03 and 1.45, 0.33 and 3.2, 0.10 and 3.36, 1.30 and 16.2 and 1.0 and 6.95 for226Ra,210Pb,210Po, 238U and 234Th, respectively. However, it is worth mentioning that the data from pot experiments may not represent field conditions. Liquid/solid partition coefficients (Kd)of 226Ra, U, 210Pb and 210Po for55 soils representing the dominant types of soils in Syria were also determined. Geometric means of Kd values ranged from 280 to1200, 750 to1600, 350to 4800 and 100-120 L kg-1 for 226Ra, 238U, 210Pb and 210Po, respectively at pH = 4.0, and from 200 to 6700, 670 to 2400, 150 to 2100 and 100 to 160Lkg-1at pH = 5.5, and from 370 to 790, 130 to 550, 60 to 330 and370 to 920Lkg-1at pH = 7.0. The effects of soil mineral content, CEC, ECE, pH and soluble ions on the Kd values were investigated. In general, there were logarithmic relationships between the activity concentrations in soil and the Kd values (R2 ranged from 0.59 to 1.00 at pH 4.0). There were no relationships between the Kd values and soil pH.


Asunto(s)
Monitoreo de Radiación , Contaminantes Radiactivos del Suelo , Uranio , Radioisótopos/análisis , Suelo , Contaminantes Radiactivos del Suelo/análisis , Siria , Factor de Transferencia , Uranio/análisis
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